Topic

Comprehensive Genomic Profiling (CGP)

  • Earlier this month, FoundationOne CDx was approved to identify mutations that lead to MET exon 14 skipping in advanced non-small cell lung cancer (NSCLC) and match patients with a new targeted therapy, which was approved in parallel. This simultaneous approval presents a new treatment option for the 2-3% of lung …

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  • The Future of TMB as a Predictor of Immunotherapy Response Depends on Harmonization

    The arrival of the American Association of Cancer Research (AACR) annual meeting this week was accompanied by mixed feelings for me. AACR has always been the first big opportunity of the year for the oncology community to come together, share the latest research and debate the high-profile topics of the moment. The …

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  • Liquid Biopsy: From an Improbable Idea, New Potential Emerges

    By Prasanth Reddy, MD, MPh, FACP, VP, Medical Affairs, Foundation Medicine and Lucas Dennis, Senior Director, Franchise Development, Foundation Medicine It’s always been an ambitious concept: By analyzing a patient’s blood, doctors might better understand their individual cancer, and thus better pinpoint what …

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  • The Role of Comprehensive Genomic Profiling in Colorectal Cancer

    March is Colorectal Cancer (CRC) Awareness Month, and while CRC is an important topic of conversation year-round, this is an especially critical time to reflect on how scientific research and advancements in personalized medicine are transforming the outlook for people living with this disease. CRC is the third most …

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  • Partnerships Are Paving the Way for Improved Patient Options

    This article was originally published on LinkedIn. Over the past ten years, there has been a fundamental shift in the way cancer is being treated. Access to genomic data has evolved the way the community thinks about researching, detecting, and treating cancer. Due to this shift, the expansion of the genomic …

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  • A Year of Change and an Exciting Chapter Ahead

    This article was originally published on LinkedIn. December is always a busy time. Suddenly everyone seems to be filled with a sense of urgency and purpose as the holidays approach and the year draws to a close. There’s almost a static charge to the air; a feeling of anticipation around what the new year may bring …

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  • ASH 2019: Can Rapid Precision Medicine Help Older Adults With AML?

    When someone is diagnosed with acute myeloid leukemia (AML), doctors typically initiate treatment within 24-48 hours of diagnosis given the aggressive nature of the disease. This urgency to treat precludes the use of ancillary test results, such as genomic profiling, to guide upfront treatment decision making and …

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  • Breast cancer – a very personal history and an even more personalized future

    This article was originally published on LinkedIn. As I sat down to write this latest post, I was suddenly struck by how little I have written about breast cancer over the course of these articles. This came as quite a surprise given that breast cancer research has played an important, if not always welcome part in …

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  • Uncovering Insights in Pancreatic and Prostate Cancers

    Most know a pancreatic cancer diagnosis is devastating. We’ve seen Patrick Swayze, Michael Landon, and Steve Jobs taken too soon by this terrible disease. We know survival is rare. Only 9 percent of patients live five years after diagnosis.1 Many may not realize, however, that prostate cancer can also be devastating, …

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  • Recognizing Value Through Collaboration

    As adoption of comprehensive genomic profiling (CGP) becomes more widespread in cancer treatment, new research is redefining the clinical utility of diagnostic tests in this age of precision medicine. The value of CGP lies in helping to inform decisions on available treatment options, including clinical trial …

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  • The oncology community is gearing up for the largest gathering of the year, the American Society of Clinical Oncology Annual Meeting (ASCO), which will take place June 3-7 in Chicago. The meeting is a critically important annual gathering of thousands of experts where the latest scientific breakthroughs and exciting …

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  • A new study published in the April 16 edition of The Oncologist reveals that the majority of gastric cancers harbor at least one clinically relevant genomic alteration, demonstrating the utility of comprehensive genomic profiling to match patients to targeted therapy options and relevant clinical trials. Gastric …

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